Fowler Fitness
patreon
Underground supplements for endurance athletes and glycolytic sports
🕑 Added 2024-05-24 00:33:37 +0000 UTCMetaprot (bemethyl)
Metaprot, also known as Bemethyl, is an actoprotector that falls under the category of a synthetic adaptogen. It’s one of my all time favorite supplements witha significant capacity to enhancephysical performance. It is approved for use in Ukraine as a dietary supplement (despite being labeled as a drug in other countries) and is commonly utilized by Ukrainian national sport teams for preparation for international competition and was also use by soldiers in Iraq to help them adapt to the hot tempature. Metaprot acts as an antihypoxant, antioxidant, and antimutagenic. It helps combat conditions of hypoxia, increase physical performance, and enhance the body's resistance to extreme factors like physical activity, stress, high altitudes and extreme heat. Overheating is a big component of poor performance. time to exhuasation significantly increases in direct proportion to increases in core body temperature. Metaprot was something I used frequently when I was training clients in my garage for 8 hours a day in 105 degree heat. It’s a really unique supplement with benefits that few compounds have to offer
Dosage: 500-750mg 5x a week, 2 days off. Cycle off after 3-4 weeks
https://cosmicnootropic.com/products/bemitil/
Emoxypine
Emoxypine, also known as Mexidol, is a Russian antioxidant with a chemical structure similar to Vitamin B6. Its neuroprotective, anti-stress, and anti-inflammatory as well. While emoxypine has a variety of benefits, one of its main proposed theoretical benefits for endurance arhketes is it’s ability to protect the heart from ischemia by improving blood flow and cardiac contracility.
The recommended dosage can vary but typically ranges from 125mg to 250mg per day.
https://cosmicnootropic.com/instructions/mexidol-emoxypine-pills-instruction/
High Dose Ubiquinol:
Ubiquinol (or COQ10) is a crucial antioxidant that plays a big role in cellular energy production. It helps in the transfer of electrons in the mitochondria, particularly in organs like the heart.
Ideal dosing is 300-600mg
Glycerol Monostearate
Glycerol Monostearate is a compound commonly used in food and cosmetic products. glycerol monostearate may help with improving hydration and endurance in athletes by supra-hydrating cells. This is because glycerol monostearate is a hygroscopic substance, meaning it attracts and retains water. GM enters the bloodstream and tissues, where it draws water and minerals into the cells through osmosis. This process increases the water content within the cells, leading to cell ‘hyper hydration’ and improved exercise tolerance
The dosing of glycerol monostearate often range from 1 to 3 grams per day.
Highly branched Dextrin
HBCD is a type of carbohydrate that is commonly used as a source of energy for athletes during intense and prolonged exercise. HBCD has a high molecular weight and low osmolarity, meaning that it allows for super quick digestion and absorption, providing a sustained release of energy. HBCD is fairly well known for its ability to enhance athletic performance, reduce fatigue, and support glycogen replenishment. The recommended dosing of HBCD for endurance athletes typically ranges from 30 to 60 grams per hour of exercise and this stacks extremely with glycerol
https://www.amazon.com/True-Nutrition-Cutting-Edge-Carbohydrate-Intra-Workout/
Mildronate
Mildronate (aka Meldonium) is a Russian medication and performance drug that is used to treat heart conditions and improve blood flow. It has gained attention for its potential performance-enhancing benefits. (It has been banned in certain sports competitions, mostly in Europe though. Something to keep in mind even though it’s super safe). Mildronate is believed to have benefits for endurance athletes by increasing oxygen delivery to tissues, enhancing endurance, and potentially improving recovery and cardiac function.
https://cosmicnootropic.com/products/mildronate-meldonium/
Oral (or injectable) L-carnatine
L-carnatine is a popular supplement with some well documented benefits for endurance activities. carnitine helps transport fatty acids into the mitochondria, where they can be burned for energy. This can help improve your body's ability to use fat as a fuel source, which is particularly beneficial during long-duration, low-to-moderate intensity exercise. L carnatine is well stacked with ubiquinol and D-ribose.
It’s best done as an injection but can also be taken in capsule form around 2-3 g before exercise.
D-ribose
Endurance activity puts significant metabolic demands on the heart, leading to the depletion of out nucleotide pool, primarily ATP. During prolonged endurance activities, the heart works harder to pump blood and deliver oxygen and nutrients to muscles. This increased workload requires a substantial amount of ATP. While the body does has mechanisms to resynthesize ATP, the rate of ATP usage during intense endurance exercise can outpace the rate of ATP production, especially in the heart. Some of the breakdown products, such as adenosine, can be lost from the cells, leading to a further depletion of the nucleotide pool. This loss is particularly critical because it affects the cell's ability to quickly regenerate ATP. D-ribose pentose sugar that is a bi component of nucleotide structure. It plays a crucial role in the synthesis of nucleotides including ATP. By providing the ribose sugar, D-ribose facilitates the production and replenishment of ATP. This isn’t just important for performance, but it’s extremely important for keeping the heart healthy during prolonged exercise
Dosage typically ranges from 5 to 15 grams per day
Any brand works for ribose.
Nano bubble oxygen water
Recent studies have shown that nano-bubbled oxygen water can have some interesting performance enhancing benefits. While most claims regarding "oxygen-enriched water" have traditionally been regarded as a bit of a "wellness grift," some advances in nano-bubble oxygen delivery technology make this a viable strategy for improving performance, particularly in endurance athletes.
A randomized controlled trial involving male cyclists demonstrated that consumption of an oxygen-nanobubble beverage improved performance metrics during both submaximal and maximal efforts. Specifically, athletes showed a 2.4% faster completion time in a 16.1 km time trial and a 4.1% increase in average power output compared to a placebo group. Additionally, peak power during repeated high-intensity exercises increased by 7.1% following the consumption of the oxygen beverage.
The GI tract may serve as a gas exchange surface, allowing for the diffusion of oxygen readily into the bloodstream. This is particularly relevant for athletes during intense exercise when oxygen demand is acutely heightened. The bubbles in the beverage are often coated with lecithin, which may act as an oxygen carrier. This facilitates the delivery of a greater quantity of oxygen than what is initially encapsulated within the bubbles. The unique properties of nanobubbles, which are significantly smaller than traditional bubbles, allow for a more stable and effective suspension in liquids as well. Nano bubbles are much smaller than regular bubbles, typically measuring less than 200 nanometers in diameter. This allows them to remain suspended in liquids for extended periods without rising to the surface, unlike larger bubbles that tend to coalesce and escape quickly.
Due to their unique properties, it appears that nano bubbles can potentially deliver oxygen more effectively to tissues and organs, and may even have longer lasting benefits than supplemental oxygen delivered via a cannula. This acutely lower fatigue (often up to 30min after consumption). NB oxygen water has been clinically shown to improve blood oxygen saturation and acutely lower heart rate during intense stress
How to use
Drink one serving during intense exercise. I think this could stack really well with methylene blue, since MB enhances oxygen utalization
https://inhalehydration.com/products/superoxygenated-water
Exogenous ketones
Exogenous ketones, have become a hot topic in the world of endurance sports. Athletes are increasingly interested in how these compounds can enhance performance and recovery. Let’s break down the mechanisms of action for exogenous ketones in a way that’s easy to understand.
One of the main benefits of exogenous ketones is that they provide an alternative source of energy during prolonged exercise. When you consume BHB, it enters your bloodstream and can be used by your muscles and brain as fuel. This is particularly useful during endurance activities, where glycogen stores (the body’s primary energy source) can become depleted. By tapping into ketones, athletes can potentially sustain their energy levels for longer periods, particularly during events like marathons or triathlons.
Exogenous ketones help spare glycogen, meaning they allow the body to use fat as a fuel source more efficiently. This is important because it helps preserve glycogen stores for when they are most needed, such as during the final push of a race. By promoting fat oxidation, ketones can help athletes maintain performance without relying solely on carbohydrates initially. This works even better when combined with a source of carbohydrates like highly branched dextrins. This provides the body with another fuel source to use after ketones have been burned through. Ketones also synergize with oxygen based therapies.
How are they used?
One ketone shot before an endurance activity. KetonAid is my favorite brand
Comments
Joey Coudriet
Do you know if the nano bubble sits well in the gut or could cause any upset?
Fastbonkers
if you had a field-based athletic competition would you use bemethyl or meldonium, and can you stack them? Which one would give majority of the benefits or would they be extremely strong together, Thank you
