Fowler Fitness
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Instagram Q&A 12/30/2024
🕑 Added 2024-12-31 04:22:18 +0000 UTCQ: Do you think concern over GMO food is overblown?
A: Not at all. If anything it's not discussed enough.The only people who think GE has no downsides are neo-Darwinist's who plug the central dogma of molecular biology and Mendelian genetics into every equation spanning agriculture to medicinal biotech.
Remember, the ecological whole that the organisms - and its genes - are entangled in determines how genes are subject to feedback regulation. This is true even for transgenes. A potential source of new viruses can arise through recombination. The promoter gene from the cauliflower mosaic virus which is commonly used to enhance gene expression in genetically modified crops, particularly for traits like herbicide and disease resistance can recombine with other viruses, leading to the creation of new viruses with a broader range of effects.CaMV shares tons of genetic similarities with human retroviruses, including HIV, human leukaemia viruses, and hepatitis B. CaMV promoter MIGHT have potential to facilitate the production of human viruses as well. modified crops with CaMV promoters experimentalally have been shown to also recombination with human viruses in the body.
Q: What are some low hanging fruits to hack motivation. I have the will to do things but no energy
A: That's a loaded question man. Theres a million and one different reasons why you might have low energy - Vitamin mineral deficiencies, poor stress management, too much training, brain fog from dysbiosis, poor circadian hygiene (too much blue light, not enough sunlight etc). I would suggest at the very least, getting on some magnesium and B vitamins (preferably mine since they are amazing, which you can find in the bio lol) Mitolife shilajit (aka panacea which you can find under the mitolife tab in the bio) and then singing up for the patreon and following something like the fungal protocol. That's really all I can tell you. Theres likely a ton of foundational groundwork you'd need to cover, and that would likely require one on one coaching or a consult call. At the very least, get some foundational nutrients in line, clean up diet, and try to get more sleep.
Q: Treatments for managing MS, for a top level strength athlete, any promising peptides?
A: Plasmalogen replacement therapy. I have tons of patreon articles on Where to get them and how to use them. Or even better, reach out to Dr Dayan Goodenows team directly or consider getting actual treatment at one of his regenerative health centers (I think he has one in the US and Canada). Plasmalogen replacement therapy has done some amazing things for people with MS, ALS, Parkinson's, autism and Alzheimer's. There are human clinical trials that have been conducted, as well as hundreds of great clinical case results you can find on their website.
Also, some of the animal studies that have been with plasmalogens are also really cool! I know people love to dismiss animal model data, but I think when you juxtapose that against the results seen in human trials, the range of possible applications for them really becomes apparent. There was actually one study where they treated rats with a pretty aggressive neurotoxin known to induce MS symptoms in mammals (I think it was cuprizone) and actually found that the plasnalogens could both induce remylination (in previously damaged animals AND animal that were still being treated with the toxin) as well almost entirely prevent demyelination from occurring in pre-treated animals. That's pretty crazy. That's why I don't like when people shit on supplements. I really do think the proper use of supplements will be a huge piece in the 'health maintenance equation, especially as we get progressively exposed to more and more hyper-novel challenges like pollution, xenobiotics etc in the coming decades
Q: My nutrition is fairly solid, l train, am hydrated but can still go days without going toilet...
A: Yeah. This is going to shock a lot of people, but I rarely find that a lack of good nutrition is the source of most peoples digestive issues. Now, keep in mind that I'm also biased here because I mainly work with people who come to me AFTER they've already gotten a lot of the basics (like diet, sleep, etc) in check. Diet is really important for maintaining microbial ecosystems diversity, but it usually isn’t enough to restore digestive function in people
with dysbiosis. Topical steroids, steroids in general, antibiotics ete will all necessitate a direct gut centered approach. Which is usually some sort of reinoculation with a good probiotic (particularly a spore, which you can find under the just thrive tab) and possibly some direct anti-fungals to clear things like candida (aka, fungal protocol on patreon). My diet has been mostly the same now for 12 years. Very healthy, balanced etc. diet didn't fix this for me 8 years ago. The fungal protocol did though. I was on the opposite end of the spectrum (extremely loose, mushy stool), but both constipation and looser stool can result from dysbiosis.
Q: Supplements for immune system, in the winter i feel like im always sick, so many change
A: Outside of spore based probiotics, MOST supplements for 'immunity' aren't worth spending money on. You likely have a lot of giant holes in your lifestyle, particularly surrounding inadequate sun exposure (especially if this is happening in the winter) and poor gut health. To avoid sounding like a broken record, just refer back to what I wrote on the previous story. You can have sufficent T and B cell populations, but they're not going to function properly or respond appropriately to infection if they're not being shaped by the mictobiome. A lot of immune boosting herbs like beta-glucans, astargulus etc aren't getting at this. And even things like vitamin C and zinc aren't really helping much either without the gut piece in check. Do fungal protocol, and if you live at a higher latitude, a Sperti vitamin D lamp or a reptile bulb with UVA and UVB is almost mandatory for most (unless you sub maxed all summer)
Q: Does dna from the GMO get into us?
A: We actually don't really know. Which is terrifying. Research since the 1970s has demonstrated that bacterial plasmids carrying mammalian viral genes CAN infect cultured mammalian cells. In vitro...but still. These cells can then produce the virus, despite the absence of the actual eukaryotic signals necessary for gene expression on the plasmid. That phenomenon occurs because endogenous proviruses and other genetic elements can provide those required helper functions. Bacterial viruses and baculoviruses can also be absorbed by mammalian cells. Baculovirus, in particular, is used as a gene transfer vector in human gene therapy FOR THAT REASON!! baculoviruses have also been genetically modified to enhance their effectiveness against pests and are engineered viruses used directy in GE crops. It has generally been believed that our digestive system breaks down DNA, but some studies have shown that the survival of viral DNA is in the gastrointestinal track found in mice fed DNA from a bacterial virus and retained large fragments that entered the bloodstream.
Ingested DNA was not only present in the gut cells of the mice but also in their spleen, liver, and white blood cells, I think that viral DNA detected was in something like one out of every thousand cells of if I remember correctly
Q: Do you think the body can adapt to toxins?
A: Absolutely. We see this all the time with chemotherapy in cancer cells. And while it's a particular challenge to overcome in cancer treatment, healthy cells can also do this. Especially when they're supplied with enough cellular energy to do so. cells can develop or upregulate proteins that can pump (efflux pumps) different drug and toxins out of the cell before it can exert its effects
